Energized Sparkplug vs Rune of the Poisoned Blade

Energized Sparkplug
Binds when picked up
Use: Decreases target's chance to hit with attacks by 25% for 10 sec.
Sells for 12 Silver 31 Copper to vendors
Item Level 42
CHANGED Changed in Forever: effects.

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Rune of the Poisoned Blade
Binds when picked up
Classes: Rogue
Use: Engrave your belt with the Poisoned Knife rune: Instantly throw your off-hand weapon to deal normal off-hand weapon damage with a 100% chance to apply the poison from your off-hand weapon to the target. Awards 1 combo point. Refunds 5 Energy per application of Deadly Poison on the target. Poisoned Knife benefits from all talents and effects that trigger from or modify Sinister Strike.
Use: Learning
"Teaches you a new Engraving ability."
Item Level 40

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Side by side:

Set your class weights in Preferences to see which is better for you.

Stat Energized Sparkplug Rune of the Poisoned Blade Δ
Item Level 42 40 −2
Sell Price 12s 31c −12s 31c
Binding Binds when picked up Binds when picked up

Δ is Rune of the Poisoned Blade minus Energized Sparkplug: green where Rune of the Poisoned Blade is better, red where it is worse (a lower required level is better; speed and sell price have no better side). Total Stats adds up Str, Agi, Sta, Int and Spi.

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