Deadly Poison II vs Rune of the Poisoned Blade

Deadly Poison II
Classes: Rogue
Requires Level 38
Use: Coats a weapon with poison that lasts for 30 minutes. Each strike has a 30% chance of poisoning the enemy for 36 Nature damage over 12 sec. Stacks up to 5 times on a single target. 115 charges.
Sells for 55 Copper to vendors
Item Level 38

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Rune of the Poisoned Blade
Binds when picked up
Classes: Rogue
Use: Engrave your belt with the Poisoned Knife rune: Instantly throw your off-hand weapon to deal normal off-hand weapon damage with a 100% chance to apply the poison from your off-hand weapon to the target. Awards 1 combo point. Refunds 5 Energy per application of Deadly Poison on the target. Poisoned Knife benefits from all talents and effects that trigger from or modify Sinister Strike.
Use: Learning
"Teaches you a new Engraving ability."
Item Level 40

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Side by side:

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Stat Deadly Poison II Rune of the Poisoned Blade Δ
Item Level 38 40 +2
Required Level 38 −37
Sell Price 55c −55c
Binding Binds when picked up

Δ is Rune of the Poisoned Blade minus Deadly Poison II: green where Rune of the Poisoned Blade is better, red where it is worse (a lower required level is better; speed and sell price have no better side). Total Stats adds up Str, Agi, Sta, Int and Spi.

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