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Nightglow Concoction vs Runic Stave

Nightglow Concoction
Binds when picked up
Held in Off-Hand
+3 Spirit
Sells for 6 Silver 7 Copper to vendors
Item Level 18
Runic Stave
Binds when equipped
Held in Off-Hand
+2 Stamina
+2 Spirit
Requires Level 13
Sells for 8 Silver 37 Copper to vendors
Item Level 18

Side by side:

Set your class weights in Preferences to see which is better for you.

Stat Nightglow Concoction Runic Stave Δ
Item Level 18 18 0
Required Level 13 +12
Spi +3 +2 −1
Sta +2 +2
Total Stats 3 4 +1
Sell Price 6s 7c 8s 37c +2s 30c
Binding Binds when picked up Binds when equipped

Δ is Runic Stave minus Nightglow Concoction: green where Runic Stave is better, red where it is worse (a lower required level is better; speed and sell price have no better side). Total Stats adds up Str, Agi, Sta, Int and Spi.

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