Instant Poison V vs Rune of the Gladiator

Instant Poison V
Classes: Rogue
Requires Level 52
Use: Coats a weapon with poison that lasts for 30 minutes. Each strike has a 20% chance of poisoning the enemy which instantly inflicts 62 to 80 Nature damage. 150 charges.
Sells for 1 Silver to vendors
Item Level 52
CHANGED Changed in Forever: effects.

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Rune of the Gladiator
Binds when picked up
Classes: Warrior
Use: Engrave your boots with the Gladiator Stance rune: An aggressive stance that increases damage while you are wearing a shield by 10% and increases block chance by 10%, but reduces armor by 30% and threat generated by 30%. In addition, you gain 50% increased Rage when your auto-attack damages an enemy not targeting you. While wearing a shield in Gladiator Stance, you may use all abilities that are restricted to other stances.
Use: Learning
"Teaches you a new Engraving ability."
Item Level 50

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Side by side:

Set your class weights in Preferences to see which is better for you.

Stat Instant Poison V Rune of the Gladiator Δ
Item Level 52 50 −2
Required Level 52 −51
Sell Price 1s −1s
Binding Binds when picked up

Δ is Rune of the Gladiator minus Instant Poison V: green where Rune of the Gladiator is better, red where it is worse (a lower required level is better; speed and sell price have no better side). Total Stats adds up Str, Agi, Sta, Int and Spi.

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