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Instant Poison VI vs Rune of Mark of Chaos

Instant Poison VI
Requires Level 60
Use: Coats a weapon with poison that lasts for 30 minutes. Each strike has a 20% chance of poisoning the enemy which instantly inflicts 76 to 100 Nature damage. 175 charges.
Sells for 1 Silver 25 Copper to vendors
Item Level 60
CHANGED Changed in Forever: effects.

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Rune of Mark of Chaos
Binds when picked up
Use: Engrave your cloak with the Mark of Chaos rune: Curses the target for 5 min, reducing Magic resistances by 30 and increases Magic damage taken by 4%. Only one Curse per Warlock can be active on any one target.
Use: Learning
"Teaches you a new Engraving ability."
Item Level 60
CHANGED Changed in Forever: effects.

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Side by side:

Set your class weights in Preferences to see which is better for you.

Stat Instant Poison VI Rune of Mark of Chaos Δ
Item Level 60 60 0
Required Level 60 −59
Sell Price 1s 25c −1s 25c
Binding Binds when picked up

Δ is Rune of Mark of Chaos minus Instant Poison VI: green where Rune of Mark of Chaos is better, red where it is worse (a lower required level is better; speed and sell price have no better side). Total Stats adds up Str, Agi, Sta, Int and Spi.

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